| Product Name | Wilfortrine |
|---|---|
| CAS | 37239-48-8 |
| Formula | C41H47NO20 |
| MW | 873.81 |
| Appearance | |
| Melting point | 237.5-238.0 °C |
| Boiling point | 884.4±65.0 °C | Condition: Press: 760 Torr |
| PKa | 11.52±0.70 | Condition: Most Acidic Temp: 25 °C |
| Product Name | Wilfortrine |
|---|---|
| CAS | 37239-48-8 |
| Formula | C41H47NO20 |
| MW | 873.81 |
| Appearance | |
| Melting point | 237.5-238.0 °C |
| Boiling point | 884.4±65.0 °C | Condition: Press: 760 Torr |
| PKa | 11.52±0.70 | Condition: Most Acidic Temp: 25 °C |
| Differences in Multicomponent Pharmacokinetics, Tissue Distribution, and Excretion of Tripterygium Glycosides Tablets in Normal and Adriamycin-Induced Nephrotic Syndrome Rat Models and Correlations With Efficacy and Hepatotoxicity. | ||
| Source:SCI：Frontiers in Pharmacology | Author:Wei Wu | Notes：影響因子：5.988 |
| Reference description | ||
TPL (Lot: 111,567–202,005) and irbesartan (as the IS for the MS/MS determination, Lot: 100,607–201,804) reference substances (content >99%) were obtained from National Institute for Food and Drug Control (Beijing, China). WA (Lot: wkq20040901), WFG (Lot: wkq20040804), WFT (Lot: wkq20040203), WFD (Lot: wkq20040702), and WFR (Lot: wkq20040205) reference substances (content >98%) were purchased from Sichuan Weikeqi Biological Technology Co., Ltd. (Sichuan, China). Adriamycin (ADR) hydrochloride for injection (Lot: 2007E1) was provided by Shenzhen Main Luck Pharmaceuticals Inc. (Shenzhen, China). | ||
| Wilforine, the Q-marker and PK-maker of Tripterygium glycosides tablet: Based on preparation quantitative analysis and PK-PD study | ||
| Source:SCI：PHYTOMEDICINE | Author:Xue Gao | Notes：影響因子：3.61 |
| Reference description | ||
Wilfortrine (NO. 151128), wilforine (NO. 151218), wilforgine (NO. 150922), and wilfordine (NO. 160127) reference substances (purity? > 98%) were all purchased from Sichuan Weikeqi Biological Technology Co., Ltd., tripterygium glycosides tablet samples were purchased from local pharmaceutical stores (Tianjin, China), which were produced by four manufactures (De-en De (DND) | ||
| Simultaneous determination of seven effective components of Tripterygium glycosides in human biological matrices by ultra performance liquid chromatography–triple quadrupole mass spectrometry | ||
| Source:SCI：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | Author:Xi Du | Notes：影響因子：2.813 |
| Reference description | ||
Triptolide (HPLC purity 99.49%), triptophenolide (HPLC purity 99.29%), celastrol (HPLC purity 98.33%), wilforgine (HPLC purity 99.53%), wilforine (HPLC purity 99.32%) and wilfortrine (HPLC purity 99.09%) were supplied by Weikeqi Biological Technology Co., Ltd (Sichuan, China). Wilfordine (HPLC purity 98%) was purchased from ChemFaces Biochemical Co., Ltd (Wuhan, China) and irbesartan (HPLC purity 99.8%) was used as internal standard (IS) and was obtained from National Institute for Food and Drug Control (Beijing, China). | ||
